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Filtered Search Results
Medchemexpress LLC Amino-PEG7-amine | 332941-25-0 | MFCD09752883 | 99.3% | C16H36N2O7 | 1 G
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Amino-PEG7-amine is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to selectively degrade target proteins by leveraging the intracellular ubiquitin-proteasome system, utilizing two ligands connected by a linker: one targeting an E3 ubiquitin ligase and the other a specific protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Facilitates selective protein degradation
- Applicable in cancer targeted therapy
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eMolecules 6-aminoquinoline-4-carboxylic acid | 859924-25-7 | MFCD09837175 | 1g
Pharmablock | 6-aminoquinoline-4-carboxylic acid | 1g | 551240925 | PBKR2085 | | 859924-25-7 | MFCD09837175 | 188.186 | C10H8N2O2
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Ambeed 1HImidazole2carbaldehyde
1H-Imidazole-2-carbaldehyde, 10111-08-7, 95%
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Medchemexpress LLC Ethanesulfonic acid, 2-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]- | 1817735-43-5 | 99.5% | 257.30 | 25 MG
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Amino-PEG3-C2-sulfonic acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs consist of two different ligands connected by a linker, one binding to an E3 ubiquitin ligase and the other to a target protein. They function by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Intended for research use only
- Appearance: oil, colorless to light yellow
- Target: PEGs
- Storage: -20°C under nitrogen
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Ambeed 1 3 4Oxadiazol2amine
1,3,4-Oxadiazol-2-amine, 3775-60-8, 95%
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Ambeed 3 2 9HFluoren9yl methoxy ca
3-(2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)ethoxy)propanoic acid, 1654740-73-4, 97%
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Medchemexpress LLC Amine-PEG-CH2COOH | 95.0% | 100 MG
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Amine-PEG-CH2COOH (MW 2000) is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. These PROTACs leverage the intracellular ubiquitin-proteasome system to achieve selective degradation of target proteins by facilitating the connection between an E3 ubiquitin ligase and the target protein.
- Used in the synthesis of PROTACs
- Exploits the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
- Appears as a solid with a light yellow to yellow color
- For research use only
- Store at 4°C, protected from light
- In solvent, store at -80°C for 6 months or -20°C for 1 month, protected from light
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Medchemexpress LLC Sulfo-Cy5 amine | 2183440-44-8 | 98.0% | 740.97 | C38H52N4O7S2 | 10 MG
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Sulfo-Cy5 amine is a water-soluble, near-infrared fluorescent dye containing a primary amine for covalent conjugation to electrophilic targets. Sulfonate groups increase aqueous solubility, making the dye suitable for labeling biomolecules in biological buffers and imaging applications.
- Water-soluble cyanine dye suitable for near-infrared imaging.
- Primary amine functional group enables amine-reactive conjugation.
- High purity (98.0%) supports reproducible labeling results.
- Sulfonate groups enhance solubility in aqueous media and biological buffers.
- Available in small milligram pack sizes for research-scale use.
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Medchemexpress LLC 5(6)-carboxy-2',7'-dichlorofluorescein diacetate | 127770-45-0 | 97.5% | 529.28 | C25H14Cl2O9 | 10 MG
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5(6)-Carboxy-2',7'-dichlorofluorescein diacetate is a cell-permeant fluorescent tracer used to detect reactive oxygen species (ROS) in live-cell assays. Supplied as the diacetate ester to enable cellular uptake, intracellular esterases cleave the acetate groups to yield the fluorescent carboxy-dichlorofluorescein. It is commonly used in fluorescence-based assays and live-cell imaging.
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Medchemexpress LLC Poly(oxy-1,2-ethanediyl), α-(2-aminoethyl)-ω-methoxy- | 80506-64-5 | 98.0% | (C2H4O)nC3H9NO | 250 MG
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mPEG-amine (MW 5000) is a modifier that increases the water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes by replacing the sulfonic acid portion of the dye molecule. It can also form amide bonds with carboxyl groups on the surface of microspheres through EDC and Sulfo-NHS mediation, creating a PEG coating on fluorescent microspheres for large-scale rotational cytoplasmic flow studies. This product is for research use only.
- Increases water solubility of long-wavelength voltage-sensitive dyes (VSD) or Pittsburgh (PGH) dyes
- Replaces the sulfonic acid portion of dye molecules
- Forms amide bonds with carboxyl groups on microsphere surfaces
- Creates a PEG coating on fluorescent microspheres
- Suitable for large-scale rotational cytoplasmic flow studies
- For research use only
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Medchemexpress LLC N-(ethoxycarbonylmethyl)-6-methoxyquinolinium bromide | 162558-52-3 | 99.8% | 200 MG
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MQAE is a chloride ion (Cl-) fluorescent probe designed for measuring chloride concentrations. Its fluorescence intensity decreases proportionally as chloride ion levels increase, making it suitable for various detection methods like confocal microscopy and flow cytometry (Ex/Em=350/460 nm). It exhibits high cell permeability and is intended for research use only.
- Suitable for measuring chloride concentrations
- Fluorescence intensity decreases with increasing chloride ions
- High cell permeability
- Compatible with confocal microscopy and flow cytometry
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Medchemexpress LLC ACT-1004-1239 | 2178049-58-4 | 98.8% | C27H28F2N6O3 | 1 MG
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ACT-1004-1239 is a potent, selective, orally active CXCR7 antagonist with an IC50 value of 3.2 nM. It is intended for research use only.
- Inhibits human, dog, rat, mouse, guinea pig, macaque CXCR7 with IC50s of 3.2, 2.3, 3.1, 2.3, 0.6, 1.5 nM respectively.
- Promotes oligodendrocyte precursor cell (OPC) differentiation by increasing CXCL12 levels.
- Increases plasma CXCL12 concentration in naive male DBA/1 mice.
- Reduces disease severity in MOG-induced experimental autoimmune encephalomyelitis (EAE) model.
- Increases myelination in the Cuprizone-induced demyelination model mice.
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Chemscene CHEMSCENE
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5000578733 PDE5-IN-7 25G
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Medchemexpress LLC Mal-amido-PEG12-acid | 100MG
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Mal-amido-PEG12-acid | 100MG
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Medchemexpress LLC Mal-amido-PEG12-acid | 2378428-27-2 | C34H60N2O17 | 50 MG
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Mal-amido-PEG12-acid is a PEG-based PROTAC linker suitable for synthesizing PROTACs. It functions by connecting two distinct ligands, one targeting an E3 ubiquitin ligase and the other for the specific target protein, allowing for the selective degradation of target proteins through the intracellular ubiquitin-proteasome system.
- Can be used in the synthesis of PROTACs.
- Exploits the intracellular ubiquitin-proteasome system.
- Selectively degrades target proteins.
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