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Filtered Search Results
Medchemexpress LLC Azido-PEG8-amine | 857891-82-8 | >99.9% | C18H38N4O8 | 100 MG
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Azido-PEG8-amine is a PEG-based PROTAC linker designed for the synthesis of PROTACs. It features an azide group that enables its use as a click chemistry reagent for various bioconjugation strategies.
- Functions as a click chemistry reagent
- Participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups
- Engages in strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups
- Utilized in the synthesis of PROTACs for targeted protein degradation
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Medchemexpress LLC 3,6,9,12,15,18-Hexaoxaeicosane-1,20-diamine | 76927-70-3 | ≥97.0% | 324.41 | 1 G
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Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker that can be utilized in the synthesis of PROTACs. It is intended for research use only.
- PEG-based (6 units) PROTAC linker
- Can be used in the synthesis of PROTACs
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eMolecules 1170979-26-6 | ChemScene | Methyl 6-aminoquinoline-3-carboxylate | 100mg | 687356077 | CS-0196529 | MFCD18073413 | 202.213 | C11H10N2O2
ChemScene | (S)-2-(4-Methoxyphenyl)pyrrolidine hydrochloride | 100mg | 632325640 | CS-0162093 | 1227798-73-3 | MFCD08751472 | 213.710 | C11H16ClNO
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eMolecules 1128-61-6 | 6-fluoro-2-methylquinoline | Combi-Blocks, Inc. | MFCD00041233 | 161.179 | C10H8FN | 98.000 | Cc1ccc2cc(F)ccc2n1 | 100g | 586071562
6-fluoro-2-methylquinoline | Combi-Blocks, Inc. | 1128-61-6 | MFCD00041233 | 161.179 | C10H8FN | 98.000 | Cc1ccc2cc(F)ccc2n1 | 100g | 586071562
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Medchemexpress LLC Trifluoperazine dihydrochloride | 440-17-5 | 99.98% | 10 MM 1 ML
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Trifluoperazine dihydrochloride is an antipsychotic agent that functions by blocking central dopamine receptors. It also acts as a potent alpha1-adrenergic receptor antagonist and a NUPR1 inhibitor, exhibiting anticancer activity. Furthermore, it is identified as a calmodulin inhibitor and an inhibitor of P-glycoprotein. This compound is suitable for research related to schizophrenia and has been observed to act as a reversible inhibitor of influenza virus morphogenesis.
- Antipsychotic agent
- Blocks central dopamine receptors
- Potent alpha1-adrenergic receptor antagonist
- Potent NUPR1 inhibitor
- Exhibits anticancer activity
- Calmodulin inhibitor
- Inhibitor of P-glycoprotein
- Suitable for research related to schizophrenia
- Reversible inhibitor of influenza virus morphogenesis
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Medchemexpress LLC 5-Bromoisoquinoline | 34784-04-8 | 208.06 | 50 G
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5-Bromoisoquinoline is a biochemical reagent that can be used as a biological material or organic compound for life science-related research. It is also a synthetic intermediate useful for pharmaceutical synthesis.
- Biochemical reagent
- Used as a biological material or organic compound
- Applicable in life science-related research
- Synthetic intermediate for pharmaceutical synthesis
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Medchemexpress LLC Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 | 2244602-35-3 | 98.0% | 750.84 g·mol⁻¹ | C30H58N10O12 | 25 MG
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Amine-PEG3-Lys(PEG3-N3)-PEG3-N3 is a branched polyethylene glycol (PEG) linker intended for the construction of antibody-drug conjugates (ADCs). It features a primary amine handle and two azide (N3) termini to enable click chemistry and payload attachment, with high purity and defined molecular weight for controlled bioconjugation.
- Branched PEG linker with amine and azide functional groups.
- High purity: 98.0%.
- Molecular weight: 750.84 g·mol⁻¹.
- Soluble in DMSO at approximately 100 mg/mL; ultrasonic assistance may be required.
- Storage: pure form -20°C (up to 3 years) or 4°C (up to 2 years); in solvent -80°C (up to 6 months).
- Suitable for click chemistry and payload attachment in ADC construction.
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eMolecules 1255942-06-3 | DBCO-amine | Ambeed | MFCD22380759 | 276.339 | C18H16N2O | 98.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 50mg | 682930030
DBCO-amine | Ambeed | 1255942-06-3 | MFCD22380759 | 276.339 | C18H16N2O | 98.000 | NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 50mg | 682930030
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eMolecules 1170979-26-6 | METHYL 6-AMINOQUINOLINE-3-CARBOXYLATE | AstaTech | MFCD18073413 | 202.213 | C11H10N2O2 | 95.000 | COC(=O)c1cnc2ccc(N)cc2c1 | 1g | 449771392
METHYL 6-AMINOQUINOLINE-3-CARBOXYLATE | AstaTech | 1170979-26-6 | MFCD18073413 | 202.213 | C11H10N2O2 | 95.000 | COC(=O)c1cnc2ccc(N)cc2c1 | 1g | 449771392
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Medchemexpress LLC 2-(2-methoxyethoxy)ethanamine | 31576-51-9 | MFCD09032941 | 99.9% | 119.16 g/mol | C5H13NO2 | 1 G
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m-PEG2-Amine is a methoxy-terminated polyethylene glycol (PEG2) linker bearing a terminal primary amine used for bioconjugation and medicinal chemistry. It is commonly employed as a PEG-based PROTAC linker and as a cleavable linker in antibody-drug conjugate (ADC) synthesis.
- Methoxy-terminated PEG2 spacer with a terminal primary amine.
- Suitable for PROTAC synthesis and as a cleavable ADC linker.
- Hydrophilic spacer improves solubility and flexibility of conjugates.
- High purity for reliable conjugation reactions.
- Store at 4°C and protect from light; in solution, store long-term at -80°C.
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Medchemexpress LLC 3,6,9,12,15,18-Hexaoxanonadecan-1-amine | 184357-46-8 | ≥97.0% | 10 G
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m-PEG6-Amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It is also a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins, while ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
- PEG-based PROTAC linker
- Cleavable ADC linker
- Used in the synthesis of PROTACs
- Used in the synthesis of antibody-drug conjugates (ADCs)
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Medchemexpress LLC Sulfo DBCO-amine | 2028284-70-8 | 99.00% | 10 MG
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Sulfo DBCO-amine is an alkyl chain-based PROTAC linker utilized in the synthesis of PROTACs. It functions as a click chemistry reagent, possessing a DBCO group capable of undergoing strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups. PROTACs operate by exploiting the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Alkyl chain-based PROTAC linker
- Used in the synthesis of PROTACs
- Click chemistry reagent
- Contains a DBCO group
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with azide groups
- Utilizes intracellular ubiquitin-proteasome system to degrade target proteins
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Medchemexpress LLC mPEG-amine (MW 1000) | 80506-64-5 | 99.2% | (C2H4O)nC3H9NO | 500 MG
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mPEG-amine (MW 1000) is a PEG-based PROTAC linker designed for the synthesis of PROTACs. PROTACs are compounds that connect an E3 ubiquitin ligase ligand with a target protein ligand via a linker. This mechanism exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used for the synthesis of PROTACs
- Utilizes ubiquitin-proteasome system
- Selectively degrades target proteins
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Medchemexpress LLC Amino-PEG6-amine | 76927-70-3 | ≥ 97.0% | 324.41 | 100 MG
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Amino-PEG6-amine is a PEG-based (6 units) PROTAC linker. It can be used in the synthesis of PROTACs, which are molecules that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. PROTACs achieve this by containing two different ligands connected by a linker: one ligand binds to an E3 ubiquitin ligase, and the other binds to the target protein.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
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eMolecules 104530-79-2 | (S)-Tetrahydrofuran-3-amine | Accela ChemBio (ASD) | MFCD08234425 | 87.122 | C4H9NO | 97.000 | N[C@H]1CCOC1 | 1g | 724424962
(S)-Tetrahydrofuran-3-amine | Accela ChemBio (ASD) | 104530-79-2 | MFCD08234425 | 87.122 | C4H9NO | 97.000 | N[C@H]1CCOC1 | 1g | 724424962
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